Which factor is NOT associated with the age-related risk for diabetes mellitus?

In the context of age-related risk factors for diabetes mellitus, increased physical activity is not associated with that risk. In fact, regular physical activity is generally linked to a decreased risk of developing diabetes. Physical activity helps improve insulin sensitivity, aids weight management, and supports overall metabolic health.

In contrast, increased leptin levels, reduction in pancreatic beta cell function, and obesity are all factors that contribute to a heightened risk of diabetes, particularly in the aging population. Increased leptin can indicate greater fat mass and may contribute to insulin resistance; a reduction in pancreatic beta cell function can impair insulin secretion; and obesity is a well-established risk factor that negatively impacts glucose metabolism and increases the likelihood of developing type 2 diabetes. Hence, among the options provided, increased physical activity stands out as a non-risk factor for diabetes in older adults.